CielementsMD® DNA Defense Daily Cream, a new scientific and skincare innovation, when used with sunscreen, aids in the prevention of photoaging and reduces the risk of skin cancer, as demonstrated by clinical trials.
NEW YORK, May 22, 2025 — MINO Labs, LLC (“MINO Labs”), a privately held specialty pharmaceutical company, is pleased to announce the publication of a pioneering clinical study in the Journal of the American Academy of Dermatology (JAAD). The study underscores the protective advantages of its patented CannaXR™ (extended release) cannabidiol (CBD) cream.
With May being Skin Cancer Awareness Month and “Don’t Fry Day” on May 23, this scientific achievement marks the beginning of a new era in sun protection. This is especially important for promoting sun safety awareness at this time of year, providing renewed optimism in the fight against skin aging and sun-related skin cancers.
The peer-reviewed research is the first clinical trial conducted on humans to show that a topical CBD product can diminish DNA damage caused by Ultraviolet A (UVA) radiation at the cellular level. This prevents mutations in both nuclear and mitochondrial DNA, which are linked to quicker skin aging and skin cancer.
According to Dr. Adam Friedman, Professor and Chair of Dermatology at The George Washington University School of Medicine and Health Sciences and co-inventor of the Z-pod™ technology, CBD has substantial scientific support for numerous skin benefits, but its effectiveness in topical products has been limited by its ability to penetrate the skin. The Z-pods™ innovative delivery system used in this product addresses this issue, fully utilizing CBD’s incredible potential.
The complete study, entitled “Topical Nanoencapsulated Cannabidiol Cream as an Innovative Strategy Combating UVA-Induced Nuclear and Mitochondrial DNA Injury: A Pilot Randomized Clinical Study,” can be found here:.
Key Clinical Trial Results (NCT05279495):
- Obvious Protection:
- CannaXR™-treated areas showed 21% less erythema (skin redness) after being exposed to three times the UVA radiation needed to cause sunburn.
- Reduced thickening and damage to the epidermal skin (an early sign of UV skin damage).
- Fewer sunburn cells and less OGG1 staining (a biomarker indicating free radical DNA damage).
- Cellular-Level Defense:
- Reduced the anticipated harmful nuclear DNA base lesions resulting from UVA exposure.
- Significantly decreased mitochondrial DNA mutations, especially in ND1 and ND4—essential genes associated with skin aging and the risk of UV-related cancer.
According to Dr. Brian Berman, MD, PhD, principal investigator and former Vice President of the American Academy of Dermatology, this groundbreaking study marks a significant advancement in dermatological protection and anti-aging research. He stated that solutions like CannaXR™, which offer molecular protection, are crucial in the fight against skin cancer, which is still the most commonly diagnosed cancer in the United States.
The U.S. Centers for Disease Control and Prevention reports that over 6.1 million U.S. individuals are treated for basal and squamous cell carcinoma each year, costing over $8.9 billion. UVA exposure is a significant contributor to this, accelerating both visible aging and DNA damage that can lead to cancer.
CannaXR™: Where Science and Skincare Meet to Combat Sun Damage
Developed by MINO Labs, CannaXR™ combines advanced nanotechnology with cannabidiol in a new extended-release cream. It offers a novel form of topical protection, working in conjunction with sunscreen to lessen internal cellular damage. Manuel Cosme Odabachian, CEO of MINO Labs, emphasized the importance of innovative drug delivery systems in product effectiveness.
MINO Labs is dedicated to raising awareness and providing evidence-based solutions to help people better protect their skin and overall long-term health during Skin Cancer Awareness Month.
About MINO Labs
MINO Labs is a specialty pharmaceutical company that builds on two decades of dermatological innovation to create advanced wellness and protective therapies. MINO Labs, with its expanding pipeline of nanotechnology-based products, is set to revolutionize how we safeguard and maintain healthy skin.
Learn more:
Contact:
Jennifer Fisherman-Ruff
Carina Bonasera
Emily Tindol
SOURCE MINO Labs
“`